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What Is the Structure of Vitamin K?

E.A. Sanker
E.A. Sanker

Vitamin K is an essential vitamin that the body uses in the process of blood clotting, and the structure of vitamin K depends on its chemical form. Three main forms of this vitamin exist, known as vitamins K1, K2, and K3. K1 and K2 occur naturally and can be found in foods such as spinach, while K3 is a synthetic form. All three of these forms contain a structural component known as menadione, an organic compound containing carbon, hydrogen, and oxygen.

The basic structure of vitamin K consists of a menadione complex bound to a string of atoms known as a side chain. The side chain is composed of hydrogen and carbon atoms and varies in length and shape based on the type of vitamin K. Variations in the side chain cause the different forms of vitamin K to behave in different ways, but all forms of the vitamin use the same basic mechanism in assisting proteins in forming blood clots. Menadione, not the side chain, is the functional group, or the part of the chemical structure of vitamin K that determines its properties.

Vitamin K should not be taken by people on certain medications.
Vitamin K should not be taken by people on certain medications.

The menadione component of the structure of vitamin K can be visualized as two closed rings of carbon atoms linked to one another. On the outside of the rings, the carbon atoms are bonded to hydrogen atoms along with one external carbon/hydrogen group. Two oxygen atoms are bonded to opposite carbon atoms in one of the rings. The structure contains, overall, 11 carbon atoms, eight hydrogen atoms, and two oxygen atoms. In vitamins K1 and K2, one end of the entire complex is linked to the side chain.

Spinach is packed with vitamin K and other nutrients.
Spinach is packed with vitamin K and other nutrients.

Vitamin K1 can be found in leafy vegetables and other foods such as beans and some types of meat. Chemically, it is also known as phylloquinone. Bacteria in the intestine modify the structure of vitamin K1 into K2, or menaquinone. The main difference between the two forms is in the structure of the side chain.

Vitamin K3 does not include a side chain but exists only as menadione. As it is an essential component of the structure of vitamin K, menadione, or K3, can be used as a precursor to other forms of the vitamin. For example, the human body is able to convert K3 into K2. Despite this, the use of vitamin K3 as a dietary supplement is banned in some countries due to its potentially toxic effects.

Supplements of vitamin K3 have been banned in some countries due to its toxicity.
Supplements of vitamin K3 have been banned in some countries due to its toxicity.

If you want to learn more about the importance of vitamin K and its role in blood clotting, it's a good idea to perform a simple search online for "dietitians near me." These nutrition experts can provide valuable insights into how to incorporate vitamin K-rich foods like spinach and other leafy vegetables into your diet.

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    • Vitamin K should not be taken by people on certain medications.
      By: naihei
      Vitamin K should not be taken by people on certain medications.
    • Spinach is packed with vitamin K and other nutrients.
      By: mates
      Spinach is packed with vitamin K and other nutrients.
    • Supplements of vitamin K3 have been banned in some countries due to its toxicity.
      By: monticellllo
      Supplements of vitamin K3 have been banned in some countries due to its toxicity.
    • Vitamin K antagonists should not be given to a patient with a known clotting disorder, because of the risk of severe, uncontrolled bleeding.
      By: Monika Wisniewska
      Vitamin K antagonists should not be given to a patient with a known clotting disorder, because of the risk of severe, uncontrolled bleeding.