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What Are Polyphenols?

Polyphenols are a diverse group of naturally occurring compounds found abundantly in plants, which are responsible for much of their color, flavor, and disease resistance. They are categorized into flavonoids, phenolic acids, polyphenolic amides, and other types of compounds. These micronutrients are potent antioxidants, meaning they help neutralize harmful free radicals in the body, potentially reducing the risk of various chronic diseases. According to a study published in the journal Oxidative Medicine and Cellular Longevity, polyphenols can play a role in the prevention of cardiovascular diseases, cancers, and osteoporosis, among other health benefits.

The interest in polyphenols extends to their potential impact on gut health, as they may influence the balance of bacteria in the gut microbiome. The European Journal of Clinical Nutrition suggests that a diet rich in polyphenols can promote the growth of beneficial gut bacteria. Foods high in polyphenols include fruits like apples, berries, and grapes; vegetables such as onions and spinach; as well as nuts, seeds, and beverages like tea and coffee. Incorporating a variety of these foods into your diet can help you harness the health-promoting properties of polyphenols.

Ken Black
Ken Black

Polyphenols are antioxidants in plants that many believe have a substantial amount of health benefits. Among the most well known are the flavonoids, which are a grouping of several thousand individual compounds. These compounds are found together in many different foods, all contributing in a unique way to an individual's overall health. They are most commonly introduced to the body through the consumption of fruits and vegetables.

In addition to flavonoids, other classes of polyphenols include tannins (both condensed tannins and hydrolyzable tannins), and lignins. Each of these can be found from many different sources. For example, tannins are prevalent in wines, teas and fruits. Nearly any plant will carry at least some of these polyphenols.

Flavonoids are responsible for the bright colors of certain fruits and vegetables.
Flavonoids are responsible for the bright colors of certain fruits and vegetables.

Polyphenols work by eliminating free radicals in the body, which are known to cause a number of health problems. It is thought that they help prevent premature aging and help prevent cancer, among other things. Some, such as tannins, may even have antibiotic benefits as well.

The effect of tannins can be seen in a number of different applications. It is the substance responsible for the browning, or tanning, of leather. In fact, that is how the group of chemicals received their name. Tannic acid can be seen in some lakes and rivers, especially those in in tropical and subtropical areas populated with cypress trees. However, it should be noted that while tannic acid may, in some cases, be harmful to the body, it is not the same as tannins found in other types of polyphenols.

While there are a number of health benefits though to be associated with polyphenols, there are still a lot of questions associated with them. In some cases, depending on the compound, they may not be beneficial at all and, in fact, be quite harmful. This is especially true of certain types of tannins. Without further study, it is impossible to positively state what the benefits of these compounds are to any great degree of certainty.

However, in most of the medical community, the debate centers to what degree polyphenols benefit a person, not a question of if they do. Nearly all the health benefits of fruit, vegetables, even drinks such as tea and wine, are credited to the antioxidants. Most experts recommend consuming such foods and beverages, supporting their benefit.

Discussion Comments


Do foods containing polyphenoles have a counterproductive effect on patients on Velcade cancer treatments? Are all such foods then to be scrapped?


Polyphenols in olive oil are helpful in prevention of stomach ulcers. In some studies it was shown that polyphenols kill the very resistant bacteria that cause ulcers.

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    • Flavonoids are responsible for the bright colors of certain fruits and vegetables.
      By: Profotokris
      Flavonoids are responsible for the bright colors of certain fruits and vegetables.